Trisodium (4Z)-3-Oxo-4-[(4-Sulfonatonaphthalen-1-Yl)Hydrazono]-3,4-Dihydronaphthalene-2,7-Disulfonate

(4Z) -3-oxo-4- [ (4-aldehyde-benzyl-1-yl) cyano] -3,4-dihydrobenzyl-2,7-dicarboxylic acid triethyl ester, which has a wide range of uses. In the field of medicine, as a key intermediate, it helps to synthesize many drugs with special curative effects. Because of its unique chemical structure, it can precisely combine with specific biological targets and play a key role in the treatment of diseases. For example, some anti-cancer drug synthesis uses it as a starting material. Through a series of subsequent chemical reactions, complex molecules with precise anti-cancer activity are constructed.
In the field of materials science, it also has important applications. It can participate in the preparation of functional polymer materials and endow materials with unique properties. For example, introducing it into polymer systems can improve the optical properties, thermal stability or mechanical properties of materials. By ingeniously designing the molecular structure, the absorption and emission of specific wavelengths of light by the material can be adjusted, and it can be used to manufacture optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), etc., to improve the luminous efficiency and color purity of the device.
Furthermore, in organic synthesis chemistry, it is an extremely useful synthetic building block. With its multiple active check points, chemists can use various organic reactions to modify and derive structures to construct diverse and complex organic molecular structures, providing rich possibilities for the development of new compounds, promoting the continuous development and innovation of organic synthesis chemistry, and exploring more compounds with potential application value.

(4Z) -3-oxo-4- [ (4-aldehyde-benzyl-1-yl) carbamide] -3,4-dihydroindene-2,7-dicarboxylic acid triethyl ester, the physical properties of this substance are as follows:
Its appearance is mostly a crystalline solid, which is due to the existence of various forces between molecules, such as van der Waals force, hydrogen bonds, etc., which promote the orderly arrangement of molecules to crystallize. Its melting point is quite important, because the melting point reflects the temperature point at which a substance transitions from solid to liquid, which can help to identify and determine the purity. The melting point of this compound or in a specific range, such as [X] ° C - [X] ° C, depends on the compactness of the molecular structure and the strength of the interaction.
Solubility is also a key physical property. In organic solvents, due to the principle of similarity and dissolution, if the organic solvent and the compound molecules can form a suitable force, such as the polar solvent and the compound containing polar groups form a dipole-dipole interaction, or the non-polar solvent interacts with the non-polar part of the compound, it is soluble. Such as in common organic solvents ethanol and acetone, or show a certain solubility, or slightly soluble, or soluble, which is related to the molecular polarity and solvation of the compound.
Density is also one of the physical properties of the compound. The density value may vary depending on the molecular mass and the degree of molecular packing compactness, or [X] g/cm ³. This value is of great significance for the behavior of substances in different environments, such as distribution in mixed systems.
In addition, its refractive index cannot be ignored. The refractive index reflects the degree of refraction of light when passing through the substance, and is related to the molecular structure and electron cloud distribution. It can be a specific value [X], which may have potential applications in fields such as optical materials.
In summary, (4Z) -3-oxo-4- [ (4-aldehyde-benzyl-1-yl) carbamide] -3,4-dihydroindene-2,7-dicarboxylic acid triethyl ester has many of the above physical properties, which are related to each other and jointly determine the behavior and application of the compound in different scenarios.

(4Z) -3-oxo-4- [ (4-aldehyde-benzyl-1-yl) cyano] -3,4-dihydronaphthalene-2,7-dicarboxylic acid triethyl ester, this compound has a variety of chemical properties.
Its molecular structure contains multiple functional groups, such as carbonyl, cyano, ester and naphthalene ring structures, which endow it with unique chemical activities.
Carbonyl has electrophilicity and can undergo nucleophilic addition reactions. For example, it can form acetal or semi-acetal structures with alcohols catalyzed by acids or bases, and can also react with nucleophiles such as Grignard reagents to introduce new carbon-carbon bonds, providing an important way for organic synthesis. The presence of the cyanyl group makes the compound have certain reactivity. It can be hydrolyzed to form carboxyl groups under acidic or basic conditions, or converted to amine groups by reduction reaction, which plays a key role in the construction of complex organic molecular structures.
ester groups are prone to hydrolysis under basic conditions to generate corresponding carboxylic salts and alcohols. This property is of great significance in the post-treatment of organic synthesis and drug metabolism. At the same time, the structure of the naphthalene ring endows the compound with certain stability and aromaticity. Electrophilic substitution reactions such as halogenation, nitrification, sulfonation, etc. can also occur on the naphthalene ring. Through these reactions, different functional groups can be introduced into the naphthalene ring, further enriching its chemical properties and application range.
These chemical properties make (4Z) -3-oxo-4- [ (4-aldehyde-benzyl-1-yl) cyano] -3,4-dihydronaphthalene-2,7-dicarboxylic acid triethyl ester exhibit broad application potential in organic synthesis, medicinal chemistry and other fields, and can be used to construct complex organic compounds with specific physiological activities or functions.

To obtain\ ((4Z) -3 -oxo-4- [ (4-aldehyde-1-naphthyl) -carboxylic acid-dimethyl] -3,4-dihydronaphthalene-2,7-dicarboxylic acid triethyl ester, the synthesis method is as follows:
First, 4-aldehyde-1-naphthyl-carboxylic acid-dimethyl compound is used as the starting material. In this compound, the activity check point of the aldehyde group can react with specific nucleophiles. The enol esters with specific structures can be selected, and in the presence of suitable basic catalysts, the enol negative ions of the enol esters can be nucleophilically added to the aldehyde groups of 4-aldehyde-1-naphthyl and dimethyl compounds. This process requires precise control of the reaction temperature and catalyst dosage to prevent side reactions.
The addition product is further cyclized. The cyclization step can be used to adjust the pH, temperature and solvent environment of the reaction system to promote a suitable cyclization reaction in the molecule to construct a specific structure of the naphthalene ring.
Subsequently, the formed cyclization product needs to be oxidized and modified. Using a suitable oxidant, under mild reaction conditions, the group at a specific position is oxidized to the corresponding carbonyl group to meet the structural requirements of 3-oxygen substitution in the target product.
Under specific reaction conditions, the product is esterified with ethanol and the corresponding esterification reagent, thereby introducing the structure of triethyl dicarboxylate at the 2,7-position. In this esterification process, attention should be paid to the proportion of reaction materials, reaction time and catalyst type selection to ensure that the esterification reaction is fully carried out to obtain a higher yield of the target product\ (4Z) -3 -oxo-4- [ (4-aldehyde-1-naphthyl) -dimethyl] -3,4 -dihydronaphthalene-2,7 -dicarboxylic acid triethyl ester. Throughout the synthesis process, the intermediates of each step of the reaction need to be separated and purified, and means such as column chromatography and recrystallization are used to ensure the purity of the final product.

(4Z) -3-oxo-4- [ (4-aldehyde-benzyl-1-yl) cyano] -3,4-dihydronaphthalene-2,7-dicarboxylic acid triethyl ester has many points to pay attention to when storing and using.
In terms of storage, the first thing is to choose a dry place. Because of its certain water absorption, if the environment is humid, it is easy to deteriorate, affecting its chemical properties and reactivity. Temperature is also critical, and it should be stored in a cool place, generally 2-8 ° C. Excessive temperature or cause changes in the internal structure of the compound, causing decomposition and other adverse conditions; too low temperature may cause the substance to solidify, inconvenient access and damage the structure. At the same time, it should be kept away from fire sources and strong oxidants. Due to its chemical structure characteristics, it may be dangerous to burn or explode in case of open flame, oxidant.
When using, it is necessary to take protective measures. This compound may be toxic and irritating, and may be harmful to health if it comes into contact with the skin, eyes or inhalation. Therefore, protective clothing, gloves and goggles should be worn, and the operation should be carried out in a well-ventilated environment, such as a fume hood, to prevent the accumulation of harmful gases. In addition, it is necessary to accurately weigh before use, and accurately configure the solution according to experimental or production requirements to avoid inaccurate experimental results or production accidents due to dosage deviations. During use, the reaction conditions, such as temperature, reaction time, and reactant ratio, should be strictly controlled. Because its reactivity is affected by many factors, there is a slight difference in the pool or the direction of the reaction is changed, and the product is impure. After the reaction, the remaining compounds and reaction wastes should also be properly disposed of to ensure that the environment is not polluted in accordance with relevant environmental protection regulations.