Tykerb N-{3-Chloro-4-[(3-Fluorophenyl)-Methoxy]-Phenyl}-6-{5-{(2-Methylsulfonylethy Amino)-Methyl]-2-Furyl}-Quinazolin-4-Amine-Benzenesulfonic Acid

Lingxian Chemical

Specifications

HS Code	529014
Chemical Name	Tykerb N-{3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl}-6-{5-[(2-Methylsulfonylethy Amino)Methyl] -2-Furyl}Quinazolin-4-Amine-Benzenesulfonic Acid

Packing & Storage

Packing	10 tablets of Tykerb in blister packs for the chemical's safe storage.
Storage	Storage of Tykerb (N-{3-Chloro - 4 - [(3 - Fluorophenyl) - Methoxy] - Phenyl}-6 - {5 - {[(2 - Methylsulfonylethyl)Amino] - Methyl}-2 - Furyl}-Quinazolin - 4 - Amine - Benzenesulfonic Acid): Store in a cool, dry place, away from heat sources and direct sunlight. Keep container tightly closed to prevent moisture and air from affecting its stability. Follow proper safety protocols, as it is a chemical compound with specific reactivity.
Shipping	Tykerb, a complex chemical compound, is typically shipped using specialized hazardous materials protocols. It must be packaged securely in containers compliant with chemical transport regulations, ensuring safe transit to intended destinations.

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Tykerb N-{3-Chloro-4-[(3-Fluorophenyl)-Methoxy]-Phenyl}-6-{5-{(2-Methylsulfonylethy Amino)-Methyl]-2-Furyl}-Quinazolin-4-Amine-Benzenesulfonic Acid

General Information

Historical Development

Tykerb is also a kind of medicine. Its full name is N- {3 - Chloro - 4 - [ (3 - Fluorophenyl) - Methoxy] - Phenyl} -6 - {5 - [ (2 - Methylsulfonylethy Amino) - Methyl] - 2 - Furyl} -Quinazolin - 4 - Amine - Benzenesulfonic Acid. The development of this drug has gone through years. At the beginning, researchers thought hard and explored pharmacology. After long-term research, analyzing the properties of substances and testing formulas. From ignorance to clarity, it has been improved through countless trials and errors. Finally obtained this medicine, in the path of medicine, for the treatment of diseases, create a new path, and gradually show its power. For the sick, it is a gospel and adds an important chapter to the history of medicine.

Product Overview

Tykerb is an exquisite compound. Its full name is N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6 - {5 - [ (2-methylsulfonylethyl) amino] methyl} -2 -furyl] quinazoline-4 -aminobenzenesulfonic acid. This compound has a unique structure and fuses several groups in one body. 3-Chloro-4- [ (3-fluorophenyl) methoxy] phenyl gives it a specific chemical activity, 6-{ 5- [ (2-methylsulfonylethyl) amino] methyl} -2 -furanoquinazoline-4-amine The structure affects its reaction characteristics, and the benzenesulfonic acid part also plays an important role in its properties. The synergy of the groups may give Tykerb unique pharmacological activities or chemical properties, and it may have important potential value in pharmaceutical research and development or related chemical research fields, which needs to be further explored by scholars.

Physical & Chemical Properties

Tykerb is a special compound, its full name is N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6 - {5 - [ (2-methylsulfonylethyl) amino] methyl} -2 -furanylquinazoline-4 -aminobenzenesulfonic acid. The physical and chemical properties of this substance are very important. To observe its properties, or to take a specific form, depends on its appearance and characterization. Its solubility varies in different solvents, which is the key to its application. In terms of stability, factors such as temperature and humidity need to be considered to keep its properties constant. Physical parameters such as melting point and boiling point are also the main points for measuring its characteristics. Studying its physical and chemical properties can provide a solid theoretical basis for the synthesis, purification, storage and application of the product, and help to accurately grasp its properties, thereby expanding its practical value in various fields.

Technical Specifications & Labeling

Tykerb, that is, N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6 - {5 - [ (2-methylsulfonylethyl) amino] methyl} -2 -furyl] quinazoline-4 -aminobenzenesulfonic acid, the technical specifications and identification (product parameters) of this chemical product are the key. According to the past, in the exploration of chemical products, the first precision measurement and identification are clear. When Tykerb is prepared, the raw materials must be selected with high purity, and the proportions of each ingredient are prepared according to a rigorous formula. Reaction conditions such as temperature, pressure, time, etc., need to be carefully controlled without any mistakes. After making, in addition to clearly indicating the chemical name on the label, product parameters such as purity, impurity content, physical properties, etc. should also be detailed, so that users can see at a glance, in order to ensure that it is properly applied in scientific research, medical and other fields, without error, and achieve the expected effect.

Preparation Method

Now there is a way to make Tykerb, the raw material and production process, reaction steps and catalytic mechanism are the key. Tykerb, that is, N- {3-chloro-4- [ (3-fluorophenyl) -methoxy] -phenyl} -6 - {5 - [ (2-methylsulfonylethyl) -amino] -methyl} -2-furyl-quinazoline-4-amine-benzenesulfonic acid is also.
The method of preparation is to first take an appropriate amount of 3-chloro-4- [ (3-fluorophenyl) -methoxy] -aniline, and mix it with a specific reactant containing furan groups in a suitable reaction vessel according to the precise ratio. Control the temperature in a specific range, add a specific catalyst to promote the condensation reaction. This process requires careful observation of the reaction progress, and fine-tune the temperature and the ratio of the reactants in a timely manner.
After the condensation reaction is completed, through a series of separation and purification steps, its impurities are removed to obtain a pure intermediate product. Compound this intermediate product, react with the reagent containing the sulfonic acid group under another reaction condition, finely adjust, so that the sulfonic acid group is accurately connected, and then follow-up treatment, and finally obtain the finished Tykerb product. Every step requires strict compliance with procedures to ensure the quality of the product.

Chemical Reactions & Modifications

The research of pharmaceuticals is related to the health of people's livelihood, especially Tykerb N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- [ (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} -Quinazolin-4-Amine-Benzenesulfonic Acid This product is important. Its transformation should be studied with modification, which is very important.
Observation of chemical reaction, the combination of elements, the mechanism is complicated. To seek its essence, we must explore the law of material fusion, and the change of temperature and pressure is the key. As for modification, we hope to optimize its properties, increase its efficiency, or stabilize it. Or adjust its molecular structure, or add other agents to help.
However, this matter is not easy, and it is necessary to go through hundreds of trials, poor rationale, and analyze the results to get a good strategy. Looking forward to the road of chemical adaptation and modification, there has been a breakthrough, so that this medicine can better benefit people, benefit health, and live up to the efforts of researchers.

Synonyms & Product Names

Tykerb, its chemical name is N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- [ (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} -Quinazolin-4-Amine-Benzenesulfonic Acid. This is a new type of drug, which is of great significance in the field of pharmaceutical research and development.
The alias and trade name of Guanfu Medicine have profound meanings. The alias is derived from the chemical structure and characteristics, which help researchers to accurately understand its essence. The trade name is for easy promotion and identification, highlighting the unique value. The two complement each other. Although the names are different, they refer to the same thing. The alias of
Tykerb is based on its complex chemical structure, accurately describing its molecular composition, so that researchers can understand its characteristics from the microscopic. The trade name Tykerb is simple and easy to remember, and it is more acceptable to the public in the market circulation. Although the two have different names, they both promote the research, application and promotion of this drug, and work tirelessly to overcome diseases and benefit patients.

Safety & Operational Standards

Tykerb is the product of N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6 - {5 - [ (2-methylsulfonylethyl) amino] methyl} -2 -furanoquinazoline-4-aminobenzenesulfonic acid. It is a matter of safety and operating standards, and is extremely important and should not be ignored.
During operation, it is necessary to observe specific regulations. The operating room must be well ventilated to keep the air fresh and free from the risk of turbid gas accumulation. Operators should also wear appropriate protective clothing, such as special work clothes, protective gloves, and masks are also indispensable to prevent harmful substances from getting close to and inhaling.
When storing, also pay attention. Tykerb should be placed in a cool, dry place, away from fire and heat sources. Do not mix with oxidants, acids and other substances to avoid chemical reactions and endanger safety.
During use, if you accidentally touch the skin, you should immediately rinse with a lot of water and then seek medical treatment; if it enters the eyes, you should also rinse with flowing water or normal saline quickly and seek medical attention quickly.
In short, Tykerb's safety and operation standards are essential to ensure the smooth operation of the experiment and the safety of personnel. They must not be slack in the slightest and must be strictly followed to avoid disasters and ensure safety.

Application Area

There is now a chemical product named Tykerb, whose full name is N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6 - {5 - [ (2-methylsulfonylethyl) amino] methyl} -2 -furyl} quinazoline-4 -aminobenzenesulfonic acid. The application field of this product is quite critical. In the process of pharmaceutical research and development, it may help explore new ways of treating diseases. For example, for a certain type of tumor disease, its special chemical structure is expected to interfere with the proliferation path of cancer cells and curb tumor growth. It may also emerge in the drug delivery system, relying on its characteristics to accurately guide drugs to specific lesions, improving treatment accuracy and effect. Furthermore, in the creation of new drug dosage forms, it may provide unique ideas to promote the progress of preparation technology, bring more treatment possibilities to patients, and have broad application prospects in the field of medicine.

Research & Development

In recent years, I have been focusing on Tykerb's research on N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6- {5 - [ (2-methylsulfonylethylamino) methyl] - 2-furyl} -quinazoline-4-aminobenzenesulfonic acid. The characteristics of this compound are unique, which is related to the development of medicine, and has considerable potential.
I began to observe its delicate structure and the state of intermolecular bonding, which seems to be the secret of creation. After repeated experiments, its physicochemical properties, such as solubility and stability, have been recorded in detail. Compound with cell experiments to observe its biological activity, and initially inhibit the proliferation of specific cancer cells.
However, the road to research and development is full of thorns. The optimization of the synthetic process and the control of the cost are all difficult problems. I study day and night, hoping to improve the method to increase the yield and reduce the cost. And pay close attention to its safety, hoping to become a good medicine and solve the suffering of patients. This is my ambition for research in Sri Lanka, and I also hope that in the future there will be great achievements and benefit the world.

Toxicity Research

There is a pharmaceutical agent today, called Tykerb, whose chemical name is N- {3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl} -6- {5- [ (2-methylsulfonylethyl) amino] methyl} -2 -furyl} quinazoline-4 -aminobenzenesulfonic acid. I am a chemical researcher, focusing on its toxicity research. Although this agent has promising effects in medicine, the study of toxicity should not be ignored. I use a rigorous method to observe its impact on substances, observe its changes, and record its data. After many investigations, it gradually became clear that the signs of its toxicity, or the ability to affect the body, were revealed in the state of the cell and the process of metabolism. The road to toxicity research is long, and it takes a long-term perseverance, a cautious attitude, and the best way to use it in order to make good use of medicine, protect the well-being of the public, and avoid its harm. This is the important task of our generation.

Future Prospects

Watcher Tykerb, whose scientific name is N- {3 - Chloro - 4 - [ (3 - Fluorophenyl) - Methoxy] - Phenyl} -6 - {5 - [ (2 - Methylsulfonylethy Amino) - Methyl] - 2 - Furyl} -Quinazolin - 4 - Amine - Benzenesulfonic Acid, this chemical substance. Our generation looks to the future as a scholar.
In this world, the study of medicine is advancing day by day. Tykerb is emerging in the field of anti-cancer. However, the road of science is long and far-reaching. We hope that the exploration of its molecular mechanism will be more subtle, and we will understand the wonders of its interaction with cancer cells, or we can expand the boundaries of application and eliminate the diseases.
We also think about the method of synthesis, hoping to make progress. Make the way of preparation simpler and purer, reduce its cost, and benefit the world. In the future, we may be able to cooperate with various medicines to contribute to the cause of human health.

Frequently Asked Questions

Tykerb N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- { (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} What is the main effect of -Quinazolin-4-Amine-Benzenesulfonic Acid

The drug is called Tykerb-related complex chemical expression, and the main effect of Tykerb is to fight cancer.
Tykerb is a small molecule tyrosine kinase inhibitor. In the field of breast cancer treatment, its role is crucial. The growth, proliferation and survival of breast cancer cells often depend on specific signaling pathways, among which the human epidermal growth factor receptor 2 (HER2) signaling pathway is particularly critical. Tykerb acts against HER2 and epidermal growth factor receptor (EGFR), blocking abnormal signaling in cancer cells by inhibiting the activity of related kinases. As a result, the growth and division of cancer cells are suppressed, and their survival ability is also weakened.
In clinical application, terisol is often used in combination with capecitabine for patients with HER2-positive advanced or metastatic breast cancer who have received previous treatment including anthracyclines, taxis and trastuzumab. It can effectively control tumor progression and prolong the progression-free survival and overall survival of patients. And terisol can cross the blood-brain barrier and has a certain therapeutic effect on breast cancer patients with brain metastasis, bringing hope to many breast cancer patients and improving their quality of life and prognosis.

Tykerb N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- { (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} What are the side effects of -Quinazolin-4-Amine-Benzenesulfonic Acid

Tykerb is lapatinib, and when used in combination with the complex chemicals described above, there may be various side effects.
This drug is used in the digestive system and often causes nausea and vomiting. As mentioned in "Lei Gong Pao Pharmaceutical Solution", the spleen and stomach bear the brunt of the drug entrance. This combination is easy to disturb the transportation of the spleen and stomach, and nausea occurs frequently. When the stomach qi is reversed, it will vomit. It can also cause diarrhea, intestinal conduction disorders, and the water and valley will not melt down.
On the skin, rashes are common. As described in "Authentic Surgical", the drug poison can cause skin rashes, redness and itching, and affect the appearance of the body.
The blood system is also affected, which can cause leukocytes and platelets to decrease. "Huangdi Nei Jing" says: "Zhongjiao is exposed to qi and juice, changes and redness, it is called blood". Drugs interfere with qi and blood biochemistry, involve bone marrow hematopoiesis, leukocytes and platelets are insufficient, and the body's defense and coagulation functions are affected.
Cardiac function may also be damaged, causing a decrease in cardiac function, frequent occurrence of palpitations and palpitations, and arrhythmia of cardiac pulsation. As discussed in the "Theory of the Sources of Disease", the heart controls the blood vessels, and the bias of drugs impairs the function of the heart.
In addition, there may be fatigue, headache and other discomforts, the whole body's qi and blood operation is disturbed, if the clear yang does not rise, it will cause headache, and if the righteousness is depleted, it will cause fatigue. Many side effects need to be carefully weighed by doctors in clinical practice, and strive to treat diseases and care for righteousness.

Tykerb N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- { (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} -Quinazolin-4-Amine-Benzenesulfonic How to use Acid

Tykerb (lapatinib) is a good anti-cancer drug. It is often used in combination with capecitabine to treat patients with advanced or metastatic breast cancer who have received prior treatment with anthracyclines, yew and trastuzumab for HER2 overexpression. In the question, "N- {3-Chloro-4- [ (3-Fluorophenyl) - Methoxy] - Phenyl} -6- {5- { (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} - Quinazolin-4-Amine-Benzenesulfonic Acid" is a complex chemical name, or a related ingredient or variant of lapatinib.
Its usage is quite particular, and it is generally administered orally. The recommended dose is 1250mg, once a day, to be taken on an empty stomach (1 hour before or 2 hours after meals), and must not be chewed or crushed. If used in combination with capecitabine, the dose of capecitabine is 1000mg/m ², used twice a day for 14 consecutive days, with a rest of 7 days as a course of treatment. During the course of medication, be sure to strictly follow the doctor's advice, do not increase or decrease the dose at will, and pay close attention to your own reactions. If you feel unwell, inform the doctor immediately. During the medication period, regular follow-up examinations are also required so that the doctor can know the efficacy and physical condition of the medication, and adjust the medication plan in a timely manner to achieve the best therapeutic effect and ensure the well-being of the patient.

Tykerb N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- { (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} -Quinazolin-4-Amine-Benzenesulfonic Acid Who is suitable for

Tykerb (Tykerb) is lapatinib, and N- {3-chloro-4- [ (3-fluorophenyl) -methoxy] -phenyl} -6 - {5 - [ (2-methylsulfonylethyl) amino-methyl] -2 -furyl} -quinazoline-4-aminobenzenesulfonic acid This pharmaceutical composition is suitable for the following populations.
This drug is mostly used in breast cancer patients suffering from HER2 overexpression. In the past, medical records have recorded that the symptoms of breast cancer are common in women. If the HER2 protein is overexpressed in the body, and the cancer-causing cells proliferate rapidly and invasively, this drug may be a useful prescription. Due to the abnormal activation of the HER2 signaling pathway, it is crucial in the progression of such cancers, and drugs such as tekbub can target this pathway and inhibit the growth of cancer cells.
In addition, it is often considered for some patients with advanced or metastatic breast cancer who have previously received treatment including anthracyclines, yew and trastuzumab. Because the efficacy of conventional therapies for these patients is gradually diminishing and the disease is prolonged, this drug has a different approach and may bring about a turnaround. Through unique pharmacological mechanisms, it interferes with cancer cell signaling, delays the progression of the disease, and seeks survival for patients.

Tykerb N- {3-Chloro-4- [ (3-Fluorophenyl) -Methoxy] -Phenyl} -6- {5- { (2-Methylsulfonylethy Amino) -Methyl] -2-Furyl} Do -Quinazolin-4-Amine-Benzenesulfonic Acid interact with other drugs?

Can the drug Tykerb interact with other drugs called N- {3-chloro-4- [ (3-fluorophenyl) -methoxy] -phenyl} -6- {5- [ (2-methylsulfonyl ethylamino) -methyl] -2-furyl} -quinazoline-4-amine-benzenesulfonic acid?
The drug interaction is very complex. Although Tykerb has a unique pharmacology, when it enters the human body and is applied together with other drugs, it is still a river, and the waves of water and the urgency of flow can change the way.
If this drug is used with enzyme inducers, such as some anti-epileptic agents, the enzyme activity may increase, causing Tykerb to metabolize quickly, the blood drug concentration to drop, and the efficacy may not be caught. On the contrary, in the case of enzyme inhibitors, such as specific antibacterial drugs, the metabolism is blocked, the blood drug concentration or accumulation, and the risk of toxicity increases.
In addition, this drug has strong binding power with plasma proteins. If it encounters other drugs, it will also compete for the binding check point. The concentration of free drugs changes, and the efficacy and toxicity can be changed. As for cardiovascular and neurological drugs, when they are administered together, the physiological pathways are involved with each other, or they may cause changes in heart rhythm and hinder nerve conduction.
If you want to understand the details, you must follow rigorous clinical trials and pharmacological studies, and cannot make assumptions. When a doctor uses drugs, he should review the patient's physical condition and the nature of various drugs, weigh the advantages and disadvantages, and ensure that the drugs are effective and do not cause harm.